Search Result "off-target"


Research Article

Recognition of CRISPR Off-Target Cleavage Sites with SeqGAN

Journal: Current Bioinformatics
Volume: 17 Issue: 1 Year: 2022 Page: 101-107
Author(s): Wen Li,Xiao-Bo Wang,Yan Xu

Update on ICOS: A Possible Target for Turning-Off Autoimmunity

Journal: Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
Volume: 3 Issue: 3 Year: 2009 Page: 205-213
Author(s): Priya Sakthivel

Morpholino, siRNA, and S-DNA Compared: Impact of Structure and Mechanism of Action on Off-Target Effects and Sequence Specificity

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 7 Year: 2007 Page: 651-660
Author(s): James E. Summerton

Review Article

Oxidative Status in Multiple Sclerosis and Off-Targets of Antioxidants: The Case of Edaravone

Journal: Current Medicinal Chemistry
Volume: 27 Issue: 1 Year: 2020 Page: 2095-2105
Author(s): Cristina Agresti,Rosella Mechelli,Stefania Olla,Caterina Veroni,Cecilia Eleuteri,Giovanni Ristori,Marco Salvetti

Review Article

CRISPR/ Cas9 Off-targets: Computational Analysis of Causes, Prediction,Detection, and Overcoming Strategies

Journal: Current Bioinformatics
Volume: 17 Issue: 2 Year: 2022 Page: 119-132
Author(s): Roshan Kumar Roy,Ipsita Debashree,Sonal Srivastava,Narayan Rishi,Ashish Srivastava

Recent Advances in Understanding of the Immunological Off-Target Effects of siRNA

Journal: Current Gene Therapy
Volume: 11 Issue: 6 Year: 2011 Page: 532-543
Author(s): Marta Olejniczak, Katarzyna Polak, Paulina Galka-Marciniak, Wlodzimierz J. Krzyzosiak

Circulating Tumor Cells in Cancer Therapy: Are we off Target?

Journal: Current Cancer Drug Targets
Volume: 10 Issue: 5 Year: 2010 Page: 509-518
Author(s): C. Raimondi, G. Naso, A. Gradilone, W. Gianni, E. Cortesi, P. Gazzaniga

Modelling of Human Leucyl Aminopeptidases for in silico Off Target Binding Analysis of Potential Plasmodium falciparum Leucine Aminopeptidase (PfA-M17) Specific Inhibitors

Journal: Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
Volume: 8 Issue: 3 Year: 2014 Page: 191-201
Author(s): Shakti Sahi,Utkarsh Raj,Meenakshi Chaudhary,Vikrant Nain

Targeting Cancer Stem Cells: How to Switch Off Immortality

Journal: Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
Volume: 3 Issue: 3 Year: 2009 Page: 225-232
Author(s): Ana M. Prado

Mechanisms of Action of DNA-Damaging Anticancer Drugs in Treatment of Carcinomas: Is Acute Apoptosis an “Off-Target” Effect?

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1035-1039
Author(s): Aleksandra Mandic Havelka, Maria Berndtsson, Maria Hagg Olofsson, Maria C. Shoshan, Stig Linder

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