Comorbidities Inducing Mild Cognitive Impairment, an Evaluation of the Risk Caused by some Pathological Conditions

Abstract

Mild cognitive impairment has usually been associated with aging, however, in recent decades with the increase in the prevalence of pathologies such as obesity, diabetes mellitus, cardiovascular diseases, and even spinal cord injury, it has become evident that a significant percentage of people who suffer from one or more of these diseases are at greater risk of suffering from some level of cognitive impairment that can lead to the development of various types of dementia. In this chapter, we review the main characteristics and mechanisms that promote the development of this type of alteration in each of the mentioned pathologies and briefly describe the various ways in which they have been approached.

Keywords: Amnesic Memory, aging, Cognitive Domains, Diabetes Mellitus, Dysbiosis, Hypertension, Long-Term Potentiation, Low-Grade Inflammation, Mild Cognitive Impairment, Neurogenesis, Non-Amnestic Memory, Obesity, Stroke, Spinal Cord Injury.