Therapeutic Drug Targets and Phytomedicine For Triple Negative Breast Cancer

Stumbling Blocks in Reinvigorating the Health of Diseased Individuals Through Herbal Medicine

Author(s): Acharya Balkrishna, Rashmi Mittal and Vedpriya Arya * .

Pp: 198-207 (10)

DOI: 10.2174/9789815079784123010013

* (Excluding Mailing and Handling)

Abstract

Natural products exhibited a profound effect as a template or direct treatment strategy against TNBC. Implementation of natural products as a chemotherapeutic or chemo-preventive strategy faces diverse problems and challenges. Several constraints including selection, identification, and screening of bioactive components furthermore, preclinical and clinical evaluation, and approval from regulatory bodies are other hurdles to the application of phytochemicals in targeting TNBC. Although the natural metabolites possessed the substantial potential to target the disease along with reinvigorating the health of affected individuals. This chapter has highlighted the perspectives and controversies associated with herbal medicines such as consumer preferences, bio-pharmaceutics consideration, HM-HM & HM-CM interactions, and drug regulations, and discussed the need to introduce natural moieties as an alternative therapeutic approach against TNBC. 


Keywords: Biopharmaceutics, Challenges, Chemo-preventive, Phytoconstituents, Provisions, Regulations.

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