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Mini-Reviews in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

Review Article

Recent Progress on Synthesis and Anticancer Activity of 4-Thiazolidinone

Author(s): Sevil Senkardes and SG Guniz Kucukguzel

Volume 13, Issue 5, 2016

Page: [377 - 388] Pages: 12

DOI: 10.2174/1570193X13666160826154159

Price: $65

Abstract

4-Thiazolidinones are sulphur analogues of oxazolidines. They are heterocyclic ring systems which have been explored for their antimicrobial, anticancer, anti-HCV, antifungal, anticonvulsant, antituberculosis, and other activities. While some earlier reviews on the biological activities of this ring system have been reported, the present review describes more recent synthetic strategies and medicinal aspects of 4-thiazolidinones as anticancer agents reported during the past few years (2010-2016).

Keywords: 4-Thiazolidinone, anticancer activity, cytotoxic, diflunisal, etodolac, flurbiprofen, synthesis.

Graphical Abstract

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