Blood Pressure Control and Antihypertensive Treatment

Guido      Grassi; Gino      Seravalle; Fosca      Quarti Trevano; Raffaella      Dell’Oro; Giuseppe      Mancia

Abstract

Several lines of evidence show that blood pressure (BP) control in treated hypertensive patients is largely unsatisfactory and that this depends on a variety of factors, such as the poor patient’s compliance, insufficient use of combination drug treatment as well as true difficulties in achieving well controlled BP. This review article will be focused on the main features of BP control by discussing the data obtained in clinical trials as well as the results available in clinical practice. The paper will also discuss the possible factors responsible for these findings as well as the favourable outcome on cardiovascular risk profile of an effective control of elevated BP. The possible approaches for controlling elevated BP values will be highlighted.

Keywords: Hypertension, antihypertensive treatment, blood pressure control, treatment compliance, clinical trials, cardiovascular risk, ACE-inhibitor, beta-blocker, metabolic disorders, cerebrovascular disease