Abstract
Positron emission tomography (PET) has become an indispensable tool in the study of cancer biology, as well as in the clinical management of patients with cancer. Quantitative measurements of tracer accumulation enable researchers to detect tumor changes much earlier than by conventional imaging modalities. 18F-FDG has been widely utilized for staging and restaging of cancer, evaluation of response to the treatment, and assessment of prognosis; however, recently target-specific PET tracers have raised even more attention. This overview discusses the current status of PET imaging in optimization of cancer therapies in preclinical and clinical studies.
Keywords: Molecular imaging, PET, 18F-FDG, cancer therapy, cancer biology, prognosis, metastasize, CNS response, radionuclide, cell proliferation
Current Pharmaceutical Design
Title:Can PET Imaging Facilitate Optimization of Cancer Therapies?
Volume: 18 Issue: 18
Author(s): Gabriela Kramer-Marek and Jacek Capala
Affiliation:
Keywords: Molecular imaging, PET, 18F-FDG, cancer therapy, cancer biology, prognosis, metastasize, CNS response, radionuclide, cell proliferation
Abstract: Positron emission tomography (PET) has become an indispensable tool in the study of cancer biology, as well as in the clinical management of patients with cancer. Quantitative measurements of tracer accumulation enable researchers to detect tumor changes much earlier than by conventional imaging modalities. 18F-FDG has been widely utilized for staging and restaging of cancer, evaluation of response to the treatment, and assessment of prognosis; however, recently target-specific PET tracers have raised even more attention. This overview discusses the current status of PET imaging in optimization of cancer therapies in preclinical and clinical studies.
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Cite this article as:
Kramer-Marek Gabriela and Capala Jacek, Can PET Imaging Facilitate Optimization of Cancer Therapies?, Current Pharmaceutical Design 2012; 18 (18) . https://dx.doi.org/10.2174/138161212800492813
DOI https://dx.doi.org/10.2174/138161212800492813 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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