Abstract
Liraglutide is a novel glucagon-like peptide 1 analogue, which shows promise as a safe, effective therapy for type 2 diabetes. This review discusses the pathophysiology of type 2 diabetes, focusing on the incretin system, and reviews the pharmacology of liraglutide. A concise discussion of preclinical and clinical data is given, highlighting the benefits of liraglutide with respect to glycaemic control, weight modulation and extraglycaemic effects. This article also review some of recent patents related to the field.
Keywords: Liraglutide, type 2 diabetes, incretins, glucagon like peptide-1 (GLP-1)
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
Title: Liraglutide-A Novel GLP-1 Analogue
Volume: 3 Issue: 3
Author(s): Sanjay Kalra, Bharti Kalra and Amit Sharma
Affiliation:
Keywords: Liraglutide, type 2 diabetes, incretins, glucagon like peptide-1 (GLP-1)
Abstract: Liraglutide is a novel glucagon-like peptide 1 analogue, which shows promise as a safe, effective therapy for type 2 diabetes. This review discusses the pathophysiology of type 2 diabetes, focusing on the incretin system, and reviews the pharmacology of liraglutide. A concise discussion of preclinical and clinical data is given, highlighting the benefits of liraglutide with respect to glycaemic control, weight modulation and extraglycaemic effects. This article also review some of recent patents related to the field.
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Cite this article as:
Kalra Sanjay, Kalra Bharti and Sharma Amit, Liraglutide-A Novel GLP-1 Analogue, Recent Patents on Endocrine, Metabolic & Immune Drug Discovery 2009; 3 (3) . https://dx.doi.org/10.2174/187221409789104719
DOI https://dx.doi.org/10.2174/187221409789104719 |
Print ISSN 1872-2148 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3334 |
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