Abstract
Much interest has focused on the newer incretin-based therapeutic modalities for diabetes, especially GLP-1 analogues. While the comparatively older GLP-1 analogs, exenatide and liraglutide, have been discussed extensively in literature, much less is known about the newer GLP-1 analogues in the pipeline. This review focuses on the newer molecules being studied, the newer routes of administration being tried, some recent patents and potential uses for these multifaceted compounds.
Keywords: GLP-1 analogs, long acting exenatide, albiglutide, taspoglutide, GLP-2 analogs, GLP-1 secretagogues
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
Title: GLP - 1 Analogs: Newer Molecules, Newer Uses
Volume: 3 Issue: 2
Author(s): Sanjay Kalra, Bharti Kalra and Amit Kumar
Affiliation:
Keywords: GLP-1 analogs, long acting exenatide, albiglutide, taspoglutide, GLP-2 analogs, GLP-1 secretagogues
Abstract: Much interest has focused on the newer incretin-based therapeutic modalities for diabetes, especially GLP-1 analogues. While the comparatively older GLP-1 analogs, exenatide and liraglutide, have been discussed extensively in literature, much less is known about the newer GLP-1 analogues in the pipeline. This review focuses on the newer molecules being studied, the newer routes of administration being tried, some recent patents and potential uses for these multifaceted compounds.
Export Options
About this article
Cite this article as:
Kalra Sanjay, Kalra Bharti and Kumar Amit, GLP - 1 Analogs: Newer Molecules, Newer Uses, Recent Patents on Endocrine, Metabolic & Immune Drug Discovery 2009; 3 (2) . https://dx.doi.org/10.2174/187221409788452309
DOI https://dx.doi.org/10.2174/187221409788452309 |
Print ISSN 1872-2148 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3334 |
Related Articles
-
Endoplasmic Reticulum Stress, Diabetes Mellitus, and Tissue Injury
Current Protein & Peptide Science Heart Failure in North America
Current Cardiology Reviews Editorial (Thematic Issue: The Long Way to a Successful Medical Therapy of Heart Failure with Beta-blockers in Children with Heart Disease)
Reviews on Recent Clinical Trials Poly(ADP-Ribose) Polymerase Inhibitors: New Pharmacological Functions and Potential Clinical Implications
Current Pharmaceutical Design Inhibitory Effect of PD-1/PD-L1 and Blockade Immunotherapy in Leukemia
Combinatorial Chemistry & High Throughput Screening Is a "Mitochondrial Psychiatry" in the Future? A Review
Current Psychiatry Reviews Asymmetric Dimethylarginine (ADMA): A Promising Biomarker for Cardiovascular Disease?
Current Topics in Medicinal Chemistry Parvovirus B19 (B19V) Infection and Pregnancy
Current Pediatric Reviews Cell Immunity in Coronary Artery Disease (CAD)
Current Immunology Reviews (Discontinued) Celiac Disease: An Emerging Epidemic
Current Nutrition & Food Science Diagnosis and Management of Heart Failure with Preserved Ejection Fraction: 10 Key Lessons
Current Cardiology Reviews Meet Our Editorial Board Member
Current Drug Targets Proteomics and Mass Spectrometry: What Have We Learned About The Heart?
Current Cardiology Reviews Transposable Elements in Cancer and Other Human Diseases
Current Cancer Drug Targets Clinical Characteristics and Treatment of Cardiomyopathies in Children
Current Cardiology Reviews Animal Modeling of Cancer Pathology and Studying Tumor Response to Therapy
Current Drug Targets Drugs Targeting Parasite Lysosomes
Current Pharmaceutical Design Cardiotoxicity of Molecularly Targeted Agents
Current Cardiology Reviews Aldehyde Dehydrogenase-2 Roles in Ischemic Cardiovascular Disease
Current Drug Targets New Therapies to Modulate Post-Infarction Inflammatory Alterations in the Myocardium: State of the Art and Forthcoming Applications
Current Radiopharmaceuticals