Molecular Determinants that Convert Hormone Sensitive Lipase into Gibberellin Receptor

Title: Molecular Determinants that Convert Hormone Sensitive Lipase into Gibberellin Receptor

Volume: 19 Issue: 2

Author(s): Ko Hirano, Koichiro Aya, Makoto Matsuoka and Miyako Ueguchi-Tanaka

Affiliation:

Keywords: DELLA protein, gibberellin (GA), GA INSENSITIVE DWARF1 (GID1), hormone-sensitive lipase (HSL), Selaginella moellendorffii, rice, epoxidation, crystallography, Arabidopsis

Abstract: Gibberellins (GAs) are tetracyclic, diterpenoid plant hormones, essential for many developmental processes in higher plants. Plants perceive GA through a nuclear-localized GA receptor, GA INSENSITIVE DWARF1 (GID1). From sequence similarity, it is suggested that GID1 evolved from a hormone-sensitive lipase (HSL), and recent x-ray crystallography of the GA-GID1 complex has given insights into how GID1 recognizes GA. Analyses of the GA signaling pathway in several plant species further suggest that the GID1-mediated GA signaling pathway emerged in the vascular plant lineage and since then regulation of GA recognition specificity seems to have been fine tuned to strictly regulate the on – off GA signal.

Cite this article as:

Hirano Ko, Aya Koichiro, Matsuoka Makoto and Ueguchi-Tanaka Miyako, Molecular Determinants that Convert Hormone Sensitive Lipase into Gibberellin Receptor, Protein & Peptide Letters 2012; 19 (2) . https://dx.doi.org/10.2174/092986612799080248