Synthesis of Novel Tri-Arm Star Shaped 1,3,5-triazine Hydrazones from 2,4,6-tris(4-acetylphenoxy)-1,3,5-triazine Core

Title: Synthesis of Novel Tri-Arm Star Shaped 1,3,5-triazine Hydrazones from 2,4,6-tris(4-acetylphenoxy)-1,3,5-triazine Core

Volume: 9 Issue: 1

Author(s): Shrinath S. Machakanur, Basavaraj R. Patil, Dayananda S. Badiger, Aishakhanam H. Pathan, Kalagouda B. Gudasi and Sim W.A. Bligh

Affiliation:

Keywords: Cyanuric chloride, hydrazone, triazine, 2,4,6-tris(4-acetylphenoxy)-1,3,5-triazine, hyperbranched polymers, aromatic substitution, temperature, drug-conjugates, NMR, ketone

Abstract: A series of novel symmetric triazine hydrazones [N3C3(-OC6H4-p-C(CH3)=N-NH-C(O)-C6H4-p-X)3] (X = H, Br, Cl, F, OH, OCH3, CH3, NO2, NH2) were prepared in excellent yields by a three-fold condensation reaction of 2,4,6- tris(4-acetylphenoxy)-1,3,5-triazine with p-substituted benzoic acid hydrazides [NH2-NH-C(O)-C6H4-p-X]. The structures were confirmed by FT-IR, 1H, 13C, 2D-HMQC NMR and mass spectrometry (MALDI-TOF).

Cite this article as:

S. Machakanur Shrinath, R. Patil Basavaraj, S. Badiger Dayananda, H. Pathan Aishakhanam, B. Gudasi Kalagouda and W.A. Bligh Sim, Synthesis of Novel Tri-Arm Star Shaped 1,3,5-triazine Hydrazones from 2,4,6-tris(4-acetylphenoxy)-1,3,5-triazine Core, Letters in Organic Chemistry 2012; 9 (1) . https://dx.doi.org/10.2174/157017812799304051