Ritter Reaction in Subcritical Water: An Efficient and Green Method for Amides Synthesis

Title: Ritter Reaction in Subcritical Water: An Efficient and Green Method for Amides Synthesis

Volume: 9 Issue: 1

Author(s): Shengqian Jiang, Zhouyu Wang, Zhenju Jiang, Jianhui Li, Shulin Zhou and Long Pu

Affiliation:

Keywords: Alcohol, amide, nitrile, ritter reaction, subcritical water, trifluoromethanesulfonic acid, chloride, boron trifluoride, sulfuric acid, silica sulfuric acid

Abstract: Ritter reaction was carried out efficiently in subcritical water with catalytic amount of trifluoromethanesulfonic acid. The amides were formed in good to excellent yields from secondary alcohols and tert-butanol with various nitriles.

Cite this article as:

Jiang Shengqian, Wang Zhouyu, Jiang Zhenju, Li Jianhui, Zhou Shulin and Pu Long, Ritter Reaction in Subcritical Water: An Efficient and Green Method for Amides Synthesis, Letters in Organic Chemistry 2012; 9 (1) . https://dx.doi.org/10.2174/157017812799304006