Abstract
Nano Drug Delivery, as a treatment method against brain tumors, is a progressing area in the field of precise targeted drug administration methodology. The unresolved problems related to chemotherapy, other invasive therapeutic procedures and various obstructions offered by biological barriers are circumvented by nanodrug delivery. Recent dramatic developments in nanotechnology have created a lot of nano-devices which could be used against cancer. Infiltration, modulation of the Blood Brain Barrier, camouflaged from immune defense mechanism and the specific targeting of cancer affected cells are a few of the attractive features of nanodevices. We present here a review of newly evolved nanoplatforms in brain tumor therapy in which careful attention has been paid into various form nanoparticles, useful targeting ligands, altered chemotherapy agents and existing tumor therapy methods using nanotechnology.
Keywords: Brain tumor, blood brain barrier, chemotherapy, carbon nanotubes, nanoparticles, nanodrug delivery, neutron capture therapy, photodynamic therapy, RNAi, targeting ligands
Medicinal Chemistry
Title: Nanotechnology Platforms; An Innovative Approach to Brain Tumor Therapy
Volume: 7 Issue: 5
Author(s): Baiju G. Nair, Saino Hanna Varghese, Remya Nair, Yasuhiko Yoshida, Toru Maekawa and D. Sakthi Kumar
Affiliation:
Keywords: Brain tumor, blood brain barrier, chemotherapy, carbon nanotubes, nanoparticles, nanodrug delivery, neutron capture therapy, photodynamic therapy, RNAi, targeting ligands
Abstract: Nano Drug Delivery, as a treatment method against brain tumors, is a progressing area in the field of precise targeted drug administration methodology. The unresolved problems related to chemotherapy, other invasive therapeutic procedures and various obstructions offered by biological barriers are circumvented by nanodrug delivery. Recent dramatic developments in nanotechnology have created a lot of nano-devices which could be used against cancer. Infiltration, modulation of the Blood Brain Barrier, camouflaged from immune defense mechanism and the specific targeting of cancer affected cells are a few of the attractive features of nanodevices. We present here a review of newly evolved nanoplatforms in brain tumor therapy in which careful attention has been paid into various form nanoparticles, useful targeting ligands, altered chemotherapy agents and existing tumor therapy methods using nanotechnology.
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Cite this article as:
G. Nair Baiju, Hanna Varghese Saino, Nair Remya, Yoshida Yasuhiko, Maekawa Toru and Sakthi Kumar D., Nanotechnology Platforms; An Innovative Approach to Brain Tumor Therapy, Medicinal Chemistry 2011; 7 (5) . https://dx.doi.org/10.2174/157340611796799113
DOI https://dx.doi.org/10.2174/157340611796799113 |
Print ISSN 1573-4064 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6638 |
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