Abstract
Nano Drug Delivery, as a treatment method against brain tumors, is a progressing area in the field of precise targeted drug administration methodology. The unresolved problems related to chemotherapy, other invasive therapeutic procedures and various obstructions offered by biological barriers are circumvented by nanodrug delivery. Recent dramatic developments in nanotechnology have created a lot of nano-devices which could be used against cancer. Infiltration, modulation of the Blood Brain Barrier, camouflaged from immune defense mechanism and the specific targeting of cancer affected cells are a few of the attractive features of nanodevices. We present here a review of newly evolved nanoplatforms in brain tumor therapy in which careful attention has been paid into various form nanoparticles, useful targeting ligands, altered chemotherapy agents and existing tumor therapy methods using nanotechnology.
Keywords: Brain tumor, blood brain barrier, chemotherapy, carbon nanotubes, nanoparticles, nanodrug delivery, neutron capture therapy, photodynamic therapy, RNAi, targeting ligands
Medicinal Chemistry
Title: Nanotechnology Platforms; An Innovative Approach to Brain Tumor Therapy
Volume: 7 Issue: 5
Author(s): Baiju G. Nair, Saino Hanna Varghese, Remya Nair, Yasuhiko Yoshida, Toru Maekawa and D. Sakthi Kumar
Affiliation:
Keywords: Brain tumor, blood brain barrier, chemotherapy, carbon nanotubes, nanoparticles, nanodrug delivery, neutron capture therapy, photodynamic therapy, RNAi, targeting ligands
Abstract: Nano Drug Delivery, as a treatment method against brain tumors, is a progressing area in the field of precise targeted drug administration methodology. The unresolved problems related to chemotherapy, other invasive therapeutic procedures and various obstructions offered by biological barriers are circumvented by nanodrug delivery. Recent dramatic developments in nanotechnology have created a lot of nano-devices which could be used against cancer. Infiltration, modulation of the Blood Brain Barrier, camouflaged from immune defense mechanism and the specific targeting of cancer affected cells are a few of the attractive features of nanodevices. We present here a review of newly evolved nanoplatforms in brain tumor therapy in which careful attention has been paid into various form nanoparticles, useful targeting ligands, altered chemotherapy agents and existing tumor therapy methods using nanotechnology.
Export Options
About this article
Cite this article as:
G. Nair Baiju, Hanna Varghese Saino, Nair Remya, Yoshida Yasuhiko, Maekawa Toru and Sakthi Kumar D., Nanotechnology Platforms; An Innovative Approach to Brain Tumor Therapy, Medicinal Chemistry 2011; 7 (5) . https://dx.doi.org/10.2174/157340611796799113
DOI https://dx.doi.org/10.2174/157340611796799113 |
Print ISSN 1573-4064 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6638 |
Call for Papers in Thematic Issues
Carbohydrates in Computational and Medicinal Chemistry
Carbohydrates are the most essential organic molecules and are involved in the maintenance of various physiological and metabolic processes in living organisms. Carbohydrate-based compounds have come to the attention of researchers because of their significant contributions to biological functions, such as cell development and cell proliferation, connections between several cells, ...read more
Recent Advances in the Medicinal Chemistry of Cancer
Scope of the Thematic Issue: Correlation between structure and function is one of the important aspects of the success of anti-cancer compounds associated with their structure-activity interactions, physiology, biochemical, molecular, and genetic processes. Overcoming these obstacles is key to obtaining further insights into developments in rational drug design, bioorganic chemistry, ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
The Role of STAT3 Signaling in Mediating Tumor Resistance to Cancer Therapy
Current Drug Targets Immunomodulatory Activity of MicroRNAs: Potential Implications for Multiple Myeloma Treatment
Current Cancer Drug Targets Patent Selections
Recent Patents on CNS Drug Discovery (Discontinued) Structure-Activity Relationship Analyses of Glycyrrhetinic Acid Derivatives as Anticancer Agents
Mini-Reviews in Medicinal Chemistry TGFb and its Smad Connection to Cancer
Current Genomics Impaired Expression and Function of Cancer-Related Enzymes by Anthocyans: An Update
Current Enzyme Inhibition Radioprotective Gene Therapy
Current Gene Therapy Cancer and Aids: New Trends in Drug Design and Chemotherapy
Current Computer-Aided Drug Design The Safety of the Temozolomide in Patients with Malignant Glioma
Current Drug Safety Anticancer Natural Products with Collateral Sensitivity: A Review
Mini-Reviews in Medicinal Chemistry The Role of Glioma Microenvironment in Immune Modulation: Potential Targets for Intervention
Letters in Drug Design & Discovery Adrenomedullin and Nitric Oxide: Implications for the Etiology and Treatment of Primary Brain Tumors
CNS & Neurological Disorders - Drug Targets PREFACE
Anti-Cancer Agents in Medicinal Chemistry Targeting Angiogenesis in Head and Neck Cancer
Current Cancer Drug Targets Exploring the Nucleolar Proteome: Novel Concepts for Chaperone Trafficking and Function
Current Proteomics Glutathione-Triggered Drug Release from Nanostructures
Current Topics in Medicinal Chemistry Detection of Predictive Markers for Therapeutic Stratification of Salivary Glands Tumors
Current Drug Targets Heterologous Production of Death Ligands’ and Death Receptors’ Extracellular Domains: Structural Features and Efficient Systems
Protein & Peptide Letters Imaging Findings of Primary Non-functioning Hepatic Paraganglioma: A Case Report
Current Medical Imaging Macrophage Derived Cystatin B/Cathepsin B in HIV Replication and Neuropathogenesis
Current HIV Research