Abstract
In regard of increasing rates of post-stroke mood disorders and evidences of a neuroprotective effect of antbiotics after cerebral ischemia we have reviewed the clinical relevance of the neuroprotective and mood stabilizing effects of antibiotics in the light of the basic pathophsiology of depression.
Keywords: Cerebral ischemia, post-stroke mood disorders, neuroprotection, antibiotics, pathophsiology, depression, antidepressant effects, minocycline, mTOR
Mini-Reviews in Medicinal Chemistry
Title: Towards A Multimodal Treatment of Depression: A Minireview on the Potential Role of Antibiotics
Volume: 11 Issue: 11
Author(s): B. Yulug and W.-R. Schabitz
Affiliation:
Keywords: Cerebral ischemia, post-stroke mood disorders, neuroprotection, antibiotics, pathophsiology, depression, antidepressant effects, minocycline, mTOR
Abstract: In regard of increasing rates of post-stroke mood disorders and evidences of a neuroprotective effect of antbiotics after cerebral ischemia we have reviewed the clinical relevance of the neuroprotective and mood stabilizing effects of antibiotics in the light of the basic pathophsiology of depression.
Export Options
About this article
Cite this article as:
Yulug B. and Schabitz W.-R., Towards A Multimodal Treatment of Depression: A Minireview on the Potential Role of Antibiotics, Mini-Reviews in Medicinal Chemistry 2011; 11 (11) . https://dx.doi.org/10.2174/138955711797068418
DOI https://dx.doi.org/10.2174/138955711797068418 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
Call for Papers in Thematic Issues
Bioprospecting of Natural Products as Sources of New Multitarget Therapies
According to the Convention on Biological Diversity, bioprospecting is the exploration of biodiversity and indigenous knowledge to develop commercially valuable products for pharmaceutical and other applications. Bioprospecting involves searching for useful organic compounds in plants, fungi, marine organisms, and microorganisms. Natural products traditionally constituted the primary source of more than ...read more
Computational Frontiers in Medicinal Chemistry
The thematic issue "Computational Frontiers in Medicinal Chemistry" provides a robust platform for delving into state-of-the-art computational methodologies and technologies that significantly propel advancements in medicinal chemistry. This edition seeks to amalgamate top-tier reviews spotlighting the latest trends and breakthroughs in the fusion of computational approaches, including artificial intelligence (AI) ...read more
Natural Products and Dietary Supplements in Alleviation of Metabolic, Cardiovascular, and Neurological Disorders
Metabolic disorders like diabetes, obesity, inflammation, oxidative stress, cancer etc, cardiovascular disorders like angina, myocardial infarction, congestive heart failure etc as well as neurological disorders like Alzheimer?s, Parkinson?s, Epilepsy, Depression, etc are the global burden. They covered the major segment of the diseases and disorders from which the human community ...read more
Natural Products in Drug Discovery
Natural products have always been one of the important ways of drug discovery due to their novel skeleton and diverse functional group characteristics. According to statistics, between 1981 and 2019, the FDA approved a total of 1,394 small molecule drugs for marketing, of which 930 marketed drugs originated from the ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Patent Selections:
Recent Patents on Biomarkers Pediatric Catatonia: Updating An Old Syndrome in Young People
Current Psychiatry Reviews Editorial (Thematic Issue: Epilepsy and Its Therapy: Present and Future)
Current Medicinal Chemistry Peroxisome Proliferator-Activated Receptor-γ and Its Ligands in the Treatment of Tumors in the Nervous System
Current Stem Cell Research & Therapy Protective Effects of Melatonin and Mitochondria-targeted Antioxidants Against Oxidative Stress: A Review
Current Medicinal Chemistry Experimental Methods and Transport Models for Drug Delivery Across the Blood-Brain Barrier
Current Pharmaceutical Biotechnology Deciphering the Physiology Underlying the Rapid Clinical Effects of Perispinal Etanercept in Alzheimers Disease
Current Alzheimer Research Autophagy after Subarachnoid Hemorrhage: Can Cell Death be Good?
Current Neuropharmacology Current and Potential Anticancer Drugs Targeting Members of the UHRF1 Complex Including Epigenetic Modifiers
Recent Patents on Anti-Cancer Drug Discovery Histamine H4 Receptor: A Novel Target for Inflammation Therapy
Mini-Reviews in Medicinal Chemistry Chelating Agents for Metal Intoxication
Current Medicinal Chemistry Anti-Inflammatory Effects of C-Peptide Prevent Endothelial Dysfunction in Type 1 Diabetes
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Immunotoxins and Other Conjugates: Pre-clinical Studies
Mini-Reviews in Medicinal Chemistry Naturally Occurring and Related Synthetic Cannabinoids and their Potential Therapeutic Applications
Recent Patents on CNS Drug Discovery (Discontinued) Tauopathies – Focus on Changes at the Neurovascular Unit
Current Alzheimer Research Recent Updates on the Association Between Alzheimer’s Disease and Vascular Dementia
Medicinal Chemistry Omega-3 Polyunsaturated Fatty Acids and Depression: A Review of the Evidence
Current Pharmaceutical Design Acute and Chronic Stress-Induced Disturbances of Microglial Plasticity, Phenotype and Function
Current Drug Targets Targeted Drug Delivery: Trends and Perspectives
Current Drug Delivery Towards an Integrated Clinical Psychobiology of Alcoholism
Current Psychiatry Reviews