Abstract
EIPL (extensive intra-operative peritoneal lavage) therapy was developed as a prophylactic strategy for peritoneal recurrence, with the goal of improving the quality of life and survival span for advanced gastric cancer patients with peritoneal free cancer cells. The purpose of this article is to review the therapys contribution to a remarkable improvement in the 5-year survival for patients with positive lavage cytology on prospective randomized controlled clinical trials. We also advocate for the adoption of the EIPL as the optimal treatment protocol for advanced gastric cancer.
Keywords: Clinical trial, EIPL, gastric cancer, intra-peritoneal free cancer cells, peritoneal recurrence, RT-PCR, survival, EIPL (extensive intra-operative peritoneal lavage), prophylactic strategy, intra-peritoneal chemotherapy (IPC), (EIPL-IPC) group, peritoneal metastasis, serosa-invasive tumors
Reviews on Recent Clinical Trials
Title: Adopting Extensive Intra-operative Peritoneal Lavage (EIPL) as the Standard Prophylactic Strategy for Peritoneal Recurrence
Volume: 6 Issue: 3
Author(s): Shinya Shimada, Masafumi Kuramoto, Takashi Marutsuka, Yasushi Yagi and Hideo Baba
Affiliation:
Keywords: Clinical trial, EIPL, gastric cancer, intra-peritoneal free cancer cells, peritoneal recurrence, RT-PCR, survival, EIPL (extensive intra-operative peritoneal lavage), prophylactic strategy, intra-peritoneal chemotherapy (IPC), (EIPL-IPC) group, peritoneal metastasis, serosa-invasive tumors
Abstract: EIPL (extensive intra-operative peritoneal lavage) therapy was developed as a prophylactic strategy for peritoneal recurrence, with the goal of improving the quality of life and survival span for advanced gastric cancer patients with peritoneal free cancer cells. The purpose of this article is to review the therapys contribution to a remarkable improvement in the 5-year survival for patients with positive lavage cytology on prospective randomized controlled clinical trials. We also advocate for the adoption of the EIPL as the optimal treatment protocol for advanced gastric cancer.
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Cite this article as:
Shimada Shinya, Kuramoto Masafumi, Marutsuka Takashi, Yagi Yasushi and Baba Hideo, Adopting Extensive Intra-operative Peritoneal Lavage (EIPL) as the Standard Prophylactic Strategy for Peritoneal Recurrence, Reviews on Recent Clinical Trials 2011; 6 (3) . https://dx.doi.org/10.2174/157488711796575603
DOI https://dx.doi.org/10.2174/157488711796575603 |
Print ISSN 1574-8871 |
Publisher Name Bentham Science Publisher |
Online ISSN 1876-1038 |
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