Abstract
Copper perchlorate hexahydrate is found to be an efficient catalyst for the electrophilic substitution of indole with carbonyl compounds to prepare bis(indolyl)methane derivatives without solvent in excellent yield at room temperature.
Keywords: Bis(Indolyl)methanes, carbonyl compounds, Cu(ClO4)2.6H2O, indole, hexahydrate, perchlorate, Copper, alkanes, diindolylmethane, fluoroboric acid
Letters in Organic Chemistry
Title: Facile Synthesis of Bis(indolyl)alkanes Catalyzed by Cu(ClO4)2.6H2O Under Solvent Free Conditions
Volume: 8 Issue: 7
Author(s): Mukulesh Baruah
Affiliation:
Keywords: Bis(Indolyl)methanes, carbonyl compounds, Cu(ClO4)2.6H2O, indole, hexahydrate, perchlorate, Copper, alkanes, diindolylmethane, fluoroboric acid
Abstract: Copper perchlorate hexahydrate is found to be an efficient catalyst for the electrophilic substitution of indole with carbonyl compounds to prepare bis(indolyl)methane derivatives without solvent in excellent yield at room temperature.
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Cite this article as:
Baruah Mukulesh, Facile Synthesis of Bis(indolyl)alkanes Catalyzed by Cu(ClO4)2.6H2O Under Solvent Free Conditions, Letters in Organic Chemistry 2011; 8 (7) . https://dx.doi.org/10.2174/157017811796504963
DOI https://dx.doi.org/10.2174/157017811796504963 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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