Abstract
Atherosclerotic renal artery stenosis (ARAS) is a progressive disease and it is usually associated with hypertension as well as with chronic kidney and cardiovascular disease. Although the anatomical lesions are relatively easy to depict, there is need to identify diagnostic methods to establish the functional significance of the stenosis and predict the response to revascularization. Over the last years, renal revascularization appears to be increasingly performed in patients with ARAS. However, controversy abounds as so far prospective, randomised trials did not document any benefit of revascularization with or without stenting plus optimal medical treatment over optimal medical treatment alone. In this review, we discuss the current data in the field of diagnosis and management of patients with ARAS
Keywords: Atherosclerotic renal artery stenosis, renovascular hypertension, diagnosis, management, renal revascularization, cardiovascular disease, coronary heart disease, type 2 diabetes mellitus, aortic aneurysm, angiotensin receptor blocker
Current Vascular Pharmacology
Title: Atherosclerotic Renal Artery Stenosis: An Update on Diagnosis and Management
Volume: 9 Issue: 4
Author(s): Eirini Stavrinou, Charalambos Koumaras, Thomas D. Gossios, Konstantinos Tziomalos, Vasilios G. Athyros and Asterios Karagiannis
Affiliation:
Keywords: Atherosclerotic renal artery stenosis, renovascular hypertension, diagnosis, management, renal revascularization, cardiovascular disease, coronary heart disease, type 2 diabetes mellitus, aortic aneurysm, angiotensin receptor blocker
Abstract: Atherosclerotic renal artery stenosis (ARAS) is a progressive disease and it is usually associated with hypertension as well as with chronic kidney and cardiovascular disease. Although the anatomical lesions are relatively easy to depict, there is need to identify diagnostic methods to establish the functional significance of the stenosis and predict the response to revascularization. Over the last years, renal revascularization appears to be increasingly performed in patients with ARAS. However, controversy abounds as so far prospective, randomised trials did not document any benefit of revascularization with or without stenting plus optimal medical treatment over optimal medical treatment alone. In this review, we discuss the current data in the field of diagnosis and management of patients with ARAS
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Cite this article as:
Stavrinou Eirini, Koumaras Charalambos, D. Gossios Thomas, Tziomalos Konstantinos, G. Athyros Vasilios and Karagiannis Asterios, Atherosclerotic Renal Artery Stenosis: An Update on Diagnosis and Management, Current Vascular Pharmacology 2011; 9 (4) . https://dx.doi.org/10.2174/157016111796197251
DOI https://dx.doi.org/10.2174/157016111796197251 |
Print ISSN 1570-1611 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6212 |
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TREATMENT OF CARDIOVASCULAR DISEASE IN CHRONIC AND END STAGE KIDNEY DISEASE
Cardiovascular disease still remains the leading cause of death in Chronic and End Stage Kidney Disease, accounting for more than half of all deaths in dialysis patients. During the past decade, research has been focused on novel therapeutic agents that might delay or even reverse cardiovascular disease and vascular calcification, ...read more
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