Microwave Frequency Effect(s) in Organic Chemistry

Title: Microwave Frequency Effect(s) in Organic Chemistry

Volume: 8 Issue: 3

Author(s): Satoshi Horikoshi and Nick Serpone

Affiliation:

Keywords: Microwave organic synthesis, Frequency effect, 5.8 GHz, Ionic liquid, Suzuki-Miyaura coupling reaction, microwave organic synthesis apparatus, Diels-Alder reaction

Abstract: This brief article reviews the behavior of microwaves in organic syntheses from the viewpoint of the frequency effect, which has been examined on various common solvents with a newly fabricated 5.80-GHz microwave organic synthesis apparatus, whose features are compared with a similar 2.45-GHz microwave apparatus. Results from usage of the 5.80-GHz microwaves are also compared to the more frequently used MW frequency of 2.45 GHz. The frequency effect was examined for various organic reactions such as the Diels-Alder reaction, the synthesis of benzimidazole-based room-temperature ionic liquids, and the Suzuki-Miyaura coupling reaction. Non-polar solvents can prove particularly useful in organic reactions with the higher frequency microwaves. In this regard, further experiments on microwave-assisted organic syntheses will extend our understanding of the microwave frequency effect(s).

Cite this article as:

Horikoshi Satoshi and Serpone Nick, Microwave Frequency Effect(s) in Organic Chemistry, Mini-Reviews in Organic Chemistry 2011; 8 (3) . https://dx.doi.org/10.2174/157019311796197436