Abstract
An ultrasonic-assisted, one-pot, efficient, convenient procedure for the synthesis of (3-phenylisoxazol-5- yl)methanol derivatives has been developed. (3-Phenylisoxazol-5-yl)-methanol derivatives with biological and pharmaceutical property have been synthesized in moderate to excellent yields. The synthetic methods possess the advantages of high yield, facile operation process and shorter reaction time, and so on.
Keywords: Ultrasound, aldoximes, 1,3-dipolar cycloaddition, nitrile oxide, isoxazole, one-pot synthesis, pharmacophores, hydroxylamine, herbicide, phenylisoxazol
Letters in Organic Chemistry
Title: One-Pot Synthesis of (3-Phenylisoxazol-5-yl)methanol Derivatives Under Ultrasound
Volume: 8 Issue: 4
Author(s): Chuansheng Shen, Yumin Zhang, Yuanming Gan, Tianqi Zhao and Qiang Gu
Affiliation:
Keywords: Ultrasound, aldoximes, 1,3-dipolar cycloaddition, nitrile oxide, isoxazole, one-pot synthesis, pharmacophores, hydroxylamine, herbicide, phenylisoxazol
Abstract: An ultrasonic-assisted, one-pot, efficient, convenient procedure for the synthesis of (3-phenylisoxazol-5- yl)methanol derivatives has been developed. (3-Phenylisoxazol-5-yl)-methanol derivatives with biological and pharmaceutical property have been synthesized in moderate to excellent yields. The synthetic methods possess the advantages of high yield, facile operation process and shorter reaction time, and so on.
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Cite this article as:
Shen Chuansheng, Zhang Yumin, Gan Yuanming, Zhao Tianqi and Gu Qiang, One-Pot Synthesis of (3-Phenylisoxazol-5-yl)methanol Derivatives Under Ultrasound, Letters in Organic Chemistry 2011; 8 (4) . https://dx.doi.org/10.2174/157017811795371467
DOI https://dx.doi.org/10.2174/157017811795371467 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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