The First Total Synthesis of Tarennane, a Potent Antioxidant Chalcone Constituent from Tarenna Attenuate or Magnolia Officinalis

Title: The First Total Synthesis of Tarennane, a Potent Antioxidant Chalcone Constituent from Tarenna Attenuate or Magnolia Officinalis

Volume: 8 Issue: 4

Author(s): Jincheng Yang, Tao Yang, Youfu Luo, Jun He, Jianyou Shi and Aihua Peng

Affiliation:

Keywords: Tarennane, total synthesis, heck reaction, antioxidant activity, Helicobacter pylori, Alpinia rafflesiana, Cardamonin, ketone, Magnolianone, tetrabutylammonium

Abstract: The convergent total synthesis of tarennane has been accomplished in six steps starting from commercially available phloroglucinol and guaiacol; the key step of the synthesis relies on a highly regioselective Heck reaction applying iodophenol and PdCl2(PPh3)2.

Cite this article as:

Yang Jincheng, Yang Tao, Luo Youfu, He Jun, Shi Jianyou and Peng Aihua, The First Total Synthesis of Tarennane, a Potent Antioxidant Chalcone Constituent from Tarenna Attenuate or Magnolia Officinalis, Letters in Organic Chemistry 2011; 8 (4) . https://dx.doi.org/10.2174/157017811795371368