Abstract
A copper-catalyzed coupling reaction of aryl halides with various aromatic cyclic secondary amines in DMSO has been developed efficiently. The versatile and efficient copper catalyst system is of wide-spread and practical application in cross-coupling reactions.
Keywords: N-Arylation, Aromatic cyclic secondary amines, Copper catalyst, Cross-coupling, pharmaceutical, heterocycle, dioxane, toluene, dichloroethane, aryl halide
Letters in Organic Chemistry
Title: A Versatile and Efficient Cu-Catalyzed N-Arylation of Aromatic Cyclic Secondary Amines with Aryl Halides
Volume: 8 Issue: 5
Author(s): Haitao Yang, Zhiwei Miao and Ruyu Chen
Affiliation:
Keywords: N-Arylation, Aromatic cyclic secondary amines, Copper catalyst, Cross-coupling, pharmaceutical, heterocycle, dioxane, toluene, dichloroethane, aryl halide
Abstract: A copper-catalyzed coupling reaction of aryl halides with various aromatic cyclic secondary amines in DMSO has been developed efficiently. The versatile and efficient copper catalyst system is of wide-spread and practical application in cross-coupling reactions.
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Cite this article as:
Yang Haitao, Miao Zhiwei and Chen Ruyu, A Versatile and Efficient Cu-Catalyzed N-Arylation of Aromatic Cyclic Secondary Amines with Aryl Halides, Letters in Organic Chemistry 2011; 8 (5) . https://dx.doi.org/10.2174/157017811795684974
DOI https://dx.doi.org/10.2174/157017811795684974 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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