Abstract
Protein glycosylation represents one of the most important post-translational events, and is a mean of diversifying a protein without recourse to the genome. The venoms produced by snakes contain an abundance of glycoproteins with N-linked carbohydrates. N-linked glycosylation can ensure the correct folding of important functional domains. Characterization of carbohydrates structures aids in development of human therapeutics by snake venom toxins.
Keywords: N-linked oligosaccharides, snake venom, enzyme activity, serine protease
Protein & Peptide Letters
Title: Venom-Sweet-Venom: N-Linked Glycosylation in Snake Venom Toxins
Volume: 16 Issue: 8
Author(s): Sandro G. Soares and Leandro L. Oliveira
Affiliation:
Keywords: N-linked oligosaccharides, snake venom, enzyme activity, serine protease
Abstract: Protein glycosylation represents one of the most important post-translational events, and is a mean of diversifying a protein without recourse to the genome. The venoms produced by snakes contain an abundance of glycoproteins with N-linked carbohydrates. N-linked glycosylation can ensure the correct folding of important functional domains. Characterization of carbohydrates structures aids in development of human therapeutics by snake venom toxins.
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Cite this article as:
Soares G. Sandro and Oliveira L. Leandro, Venom-Sweet-Venom: N-Linked Glycosylation in Snake Venom Toxins, Protein & Peptide Letters 2009; 16 (8) . https://dx.doi.org/10.2174/092986609788923293
DOI https://dx.doi.org/10.2174/092986609788923293 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
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