Abstract
One of the main components of snake venoms are the Asp49-phospholipases A2, also known as svPLA2s. The study of these toxins is a matter of great scientific interest due to their wide variety of biological effects. In this work we present strong evidences found in literature and other aspects which strengthen the importance of quaternary assembly for understanding the activities and molecular evolution of svPLA2s.
Keywords: Phospholipase A2, oligomerization, quaternary conformation, snake venom
Protein & Peptide Letters
Title: Influence of Quaternary Conformation on the Biological Activities of the Asp49-phospholipases A2s from Snake Venoms
Volume: 16 Issue: 8
Author(s): Angelo J. Magro, Carlos A.H. Fernandes, Juliana I. dos Santos and Marcos R.M. Fontes
Affiliation:
Keywords: Phospholipase A2, oligomerization, quaternary conformation, snake venom
Abstract: One of the main components of snake venoms are the Asp49-phospholipases A2, also known as svPLA2s. The study of these toxins is a matter of great scientific interest due to their wide variety of biological effects. In this work we present strong evidences found in literature and other aspects which strengthen the importance of quaternary assembly for understanding the activities and molecular evolution of svPLA2s.
Export Options
About this article
Cite this article as:
Magro J. Angelo, Fernandes A.H. Carlos, dos Santos I. Juliana and Fontes R.M. Marcos, Influence of Quaternary Conformation on the Biological Activities of the Asp49-phospholipases A2s from Snake Venoms, Protein & Peptide Letters 2009; 16 (8) . https://dx.doi.org/10.2174/092986609788923301
DOI https://dx.doi.org/10.2174/092986609788923301 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Current Developments in the Therapeutic Potential of S-Nitrosoglutathione, an Endogenous NO-Donor Molecule
Current Pharmaceutical Biotechnology Overlooked Issues of Snakebite Management: Time for Strategic Approach
Current Topics in Medicinal Chemistry Neurokinin-1 Receptor (NK-1R) Antagonists: Potential Targets in the Treatment of Glioblastoma Multiforme
Current Medicinal Chemistry Pharmacological Risk Factors for Delirium after Cardiac Surgery: A Review
Current Neuropharmacology Psychiatric Disorders Associated with FXTAS
Current Psychiatry Reviews Interrelationships with Metabolic Syndrome, Obesity and Cardiovascular Risk
Current Vascular Pharmacology Clopidogrel, Aspirin and Proton Pump Inhibition after Percutaneous Valve Implants: An Update
Current Pharmaceutical Design Nociceptin /Orphanin FQ Peptide (NOP) Receptor Modulators: An Update in Structure-Activity Relationships
Current Medicinal Chemistry Therapy in Prion Diseases
Current Topics in Medicinal Chemistry A Practical Comprehensive Approach to Management of Acute Decompensated Heart Failure
Current Cardiology Reviews Glucose and LDL Lowering: The Need for Intensive Therapy
Current Vascular Pharmacology The Crosstalk Between Insulin and Renin-Angiotensin-Aldosterone Signaling Systems and its Effect on Glucose Metabolism and Diabetes Prevention
Current Vascular Pharmacology Herbal and Traditional Chinese Medicine for the Treatment of Cardiovascular Complications in Diabetes Mellitus
Current Diabetes Reviews Targeting TNF-Alpha to Elucidate and Ameliorate Neuroinflammation in Neurodegenerative Diseases
CNS & Neurological Disorders - Drug Targets Guide of Hypertensive Crisis Pharmacotherapy
Cardiovascular & Hematological Disorders-Drug Targets Nociceptin/Orphanin FQ Peptide Receptors: Pharmacology and Clinical Implications
Current Drug Targets Pharmacological Effects of Biotin in Animals
Mini-Reviews in Medicinal Chemistry Dopexamine After Heart Surgery: An Uncommonly Used, Though Useful Inotropic Agent
Recent Patents on Cardiovascular Drug Discovery Geriatric Psychopharmacology in Acute Settings
Current Psychopharmacology Platinum Sensor for Quantifying Caffeine in Drug Formulations
Current Pharmaceutical Analysis