Abstract
The scaled-up preparation of 1H-pyrazole, 1-phenylpyrazole and isoxazole via sonocatalysis is reported. The products were isolated in good yields in short time reaction. These compounds had been assayed for antioxidant activity by ORAC and DPPH methodologies. The results showed that only 1-phenylpyrazole presented good antioxidant activity compared with Trolox .
Keywords: Green chemistry, Isoxazole, Pyrazole, Sonocatalysis, ORAC, DPPH
Letters in Drug Design & Discovery
Title: Ultrasound Irradiation Promoted Large-Scale Preparation in Aqueous Media and Antioxidant Activity of Azoles
Volume: 6 Issue: 5
Author(s): F. A.N. Silva, M. P. Galluzzi, B. Albuquerque, L. Pizzuti, V. Gressler, D. P. Rivelli, S. B.M. Barros and C. M.P. Pereira
Affiliation:
Keywords: Green chemistry, Isoxazole, Pyrazole, Sonocatalysis, ORAC, DPPH
Abstract: The scaled-up preparation of 1H-pyrazole, 1-phenylpyrazole and isoxazole via sonocatalysis is reported. The products were isolated in good yields in short time reaction. These compounds had been assayed for antioxidant activity by ORAC and DPPH methodologies. The results showed that only 1-phenylpyrazole presented good antioxidant activity compared with Trolox .
Export Options
About this article
Cite this article as:
Silva A.N. F., Galluzzi P. M., Albuquerque B., Pizzuti L., Gressler V., Rivelli P. D., Barros B.M. S. and Pereira M.P. C., Ultrasound Irradiation Promoted Large-Scale Preparation in Aqueous Media and Antioxidant Activity of Azoles, Letters in Drug Design & Discovery 2009; 6 (5) . https://dx.doi.org/10.2174/1570180810906050323
DOI https://dx.doi.org/10.2174/1570180810906050323 |
Print ISSN 1570-1808 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-628X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers