Abstract
Neurodegenerative diseases associated with dementia are characterized by cognitive deficits and memory impairment, thus stimulating research for memory enhancing drugs. We survey here the state of the art of research and clinical trials on these drugs from cholinesterase inhibitors and drugs acting on neurotransmitter receptors to drugs acting on gene expression.
Keywords: Memory, neurodegenerative disease, acetylcholine, AMPA receptor, CREB, chromatin
Mini-Reviews in Medicinal Chemistry
Title: Memory-Enhancing Drugs: A Molecular Perspective
Volume: 9 Issue: 7
Author(s): Barbara Monti and Antonio Contestabile
Affiliation:
Keywords: Memory, neurodegenerative disease, acetylcholine, AMPA receptor, CREB, chromatin
Abstract: Neurodegenerative diseases associated with dementia are characterized by cognitive deficits and memory impairment, thus stimulating research for memory enhancing drugs. We survey here the state of the art of research and clinical trials on these drugs from cholinesterase inhibitors and drugs acting on neurotransmitter receptors to drugs acting on gene expression.
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Cite this article as:
Monti Barbara and Contestabile Antonio, Memory-Enhancing Drugs: A Molecular Perspective, Mini-Reviews in Medicinal Chemistry 2009; 9 (7) . https://dx.doi.org/10.2174/138955709788452621
DOI https://dx.doi.org/10.2174/138955709788452621 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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