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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Lactoferrin Derived Peptides: Mechanisms of Action and their Perspectives as Antimicrobial and Antitumoral Agents

Author(s): Anna Rita Lizzi, Veronica Carnicelli, Matilda M. Clarkson, Antonio Di Giulio and Arduino Oratore

Volume 9, Issue 6, 2009

Page: [687 - 695] Pages: 9

DOI: 10.2174/138955709788452757

Price: $65

Abstract

Antimicrobial peptides, AMPs, exert their function acting mainly at the membrane level. In the wide AMPs panorama a particular position is occupied by lactoferrin derived peptides. They also possess antiviral, antifungal and antitumor activities and their parent molecules are available in several mammalian fluids and in dairy industries waste.

Keywords: Antimicrobial peptides, lactoferrin, lactoferricin B, lactoferrampin


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