Abstract
Infectious diseases caused by bacteria, fungi, viruses and parasites are still a major threat to public health, despite the tremendous progress in human medicine. New antimicrobials are needed in medicine due to the rapid emergence of new resistant and opportunistic microbes and the increasing number of patients suffering from immunosuppressive situations, e.g., acquired immunodeficiency syndrome, transplantation, cancer, etc … Research on new antimicrobial substances must therefore be continued and all possible strategies should be explored. Plants have been a source of therapeutic agents from more than 5000 years. Approximately 25% of modern medications are developed from plants. In the area of infectious diseases, 75% of new drugs originated from natural sources between 1981 and 2002. As less than 10% of the worlds biodiversity has been tested for biological activity, many more useful natural lead compounds are awaiting discovery. The Cistaceae family comprises a large number of species, growing in the warm temperate regions of the Mediterranean area, that have been and are still used as medicinal plants, particularly in folk medicine. In the present review, we analyse the past, present and future of medicinal plants of the Cistaceae family present in the Iberian Peninsula, both as potential antimicrobial crude drugs as well as a source of natural compounds that act as new anti-infectious agents.
Mini-Reviews in Medicinal Chemistry
Title: Anti-Infectious Activity in the Cistaceae Family in the Iberian Peninsula
Volume: 9 Issue: 5
Author(s): Luis Miguel Bedoya, Paulina Bermejo and Maria Jose Abad
Affiliation:
Abstract: Infectious diseases caused by bacteria, fungi, viruses and parasites are still a major threat to public health, despite the tremendous progress in human medicine. New antimicrobials are needed in medicine due to the rapid emergence of new resistant and opportunistic microbes and the increasing number of patients suffering from immunosuppressive situations, e.g., acquired immunodeficiency syndrome, transplantation, cancer, etc … Research on new antimicrobial substances must therefore be continued and all possible strategies should be explored. Plants have been a source of therapeutic agents from more than 5000 years. Approximately 25% of modern medications are developed from plants. In the area of infectious diseases, 75% of new drugs originated from natural sources between 1981 and 2002. As less than 10% of the worlds biodiversity has been tested for biological activity, many more useful natural lead compounds are awaiting discovery. The Cistaceae family comprises a large number of species, growing in the warm temperate regions of the Mediterranean area, that have been and are still used as medicinal plants, particularly in folk medicine. In the present review, we analyse the past, present and future of medicinal plants of the Cistaceae family present in the Iberian Peninsula, both as potential antimicrobial crude drugs as well as a source of natural compounds that act as new anti-infectious agents.
Export Options
About this article
Cite this article as:
Bedoya Miguel Luis, Bermejo Paulina and Abad Jose Maria, Anti-Infectious Activity in the Cistaceae Family in the Iberian Peninsula, Mini-Reviews in Medicinal Chemistry 2009; 9 (5) . https://dx.doi.org/10.2174/138955709788167600
DOI https://dx.doi.org/10.2174/138955709788167600 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
Call for Papers in Thematic Issues
Bioprospecting of Natural Products as Sources of New Multitarget Therapies
According to the Convention on Biological Diversity, bioprospecting is the exploration of biodiversity and indigenous knowledge to develop commercially valuable products for pharmaceutical and other applications. Bioprospecting involves searching for useful organic compounds in plants, fungi, marine organisms, and microorganisms. Natural products traditionally constituted the primary source of more than ...read more
Computational Frontiers in Medicinal Chemistry
The thematic issue "Computational Frontiers in Medicinal Chemistry" provides a robust platform for delving into state-of-the-art computational methodologies and technologies that significantly propel advancements in medicinal chemistry. This edition seeks to amalgamate top-tier reviews spotlighting the latest trends and breakthroughs in the fusion of computational approaches, including artificial intelligence (AI) ...read more
Natural Products and Dietary Supplements in Alleviation of Metabolic, Cardiovascular, and Neurological Disorders
Metabolic disorders like diabetes, obesity, inflammation, oxidative stress, cancer etc, cardiovascular disorders like angina, myocardial infarction, congestive heart failure etc as well as neurological disorders like Alzheimer?s, Parkinson?s, Epilepsy, Depression, etc are the global burden. They covered the major segment of the diseases and disorders from which the human community ...read more
Natural Products in Drug Discovery
Natural products have always been one of the important ways of drug discovery due to their novel skeleton and diverse functional group characteristics. According to statistics, between 1981 and 2019, the FDA approved a total of 1,394 small molecule drugs for marketing, of which 930 marketed drugs originated from the ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Strategies for Rot Control of Soybean Sprouts
Recent Patents on Food, Nutrition & Agriculture The Possibilities and Pitfalls for Anti-Complement Therapies in Inflammatory Diseases
Current Drug Targets - Inflammation & Allergy Molecular Targets from VHL Studies into the Oxygen-Sensing Pathway
Current Cancer Drug Targets Von Willebrand Factor and Thrombosis: Risk Factor, Actor and Pharmacological Target
Current Vascular Pharmacology A “Cute” Desensitization of TRPV1
Current Pharmaceutical Biotechnology Metabolic Syndrome - Risk Factors for Atherosclerosis and Diabetes
Current Diabetes Reviews Strategies to Control Human Lymphatic Filarial Infection: Tweaking Host’s Immune System
Current Topics in Medicinal Chemistry Tachykinins and their Receptors in Human Malignancies
Current Drug Targets Neuroinflammation, Diabetes and COVID-19: Perspectives Coming from Ca<sup>2+</sup>/cAMP Signalling
Current Drug Research Reviews Familial Combined Hyperlipidaemia: Under - Defined and Under - Diagnosed?
Current Vascular Pharmacology BACE1 Levels Correlate with Phospho-Tau Levels in Human Cerebrospinal Fluid
Current Alzheimer Research Epigenetically - Targeted Therapies for the Treatment of Hematological Malignancies
Current Medicinal Chemistry Fundamentals of Prion Diseases and Their Involvement in the Loss of Function of Cellular Prion Protein
Protein & Peptide Letters Histone Post-translational Modifications to Target Memory-related Diseases
Current Pharmaceutical Design Biosimilars: Current Scientific and Regulatory Considerations
Current Clinical Pharmacology Expression and Function of Anti-Inflammatory Interleukins: The Other Side of the Vascular Response to Injury
Current Vascular Pharmacology Is An Oral Plant-based Vaccine against Hepatitis B Virus Possible?
Current Pharmaceutical Biotechnology Fanconi Anemia Proteins, DNA Interstrand Crosslink Repair Pathways, and Cancer Therapy
Current Cancer Drug Targets Continuous Positive Airway Pressure Treatment in Patients with Sleep Apnoea: Does it Really Improve Glucose Metabolism?
Current Diabetes Reviews COVID-19: Our Current Knowledge of Epidemiology, Pathology, Therapeutic Approaches, and Diagnostic Methods
Anti-Cancer Agents in Medicinal Chemistry