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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Prion Protein Peptides as Vaccines

Author(s): M. Ghielmetti, T. Vranac and V. Curin Serbec

Volume 9, Issue 4, 2009

Page: [470 - 480] Pages: 11

DOI: 10.2174/138955709787847903

Price: $65

Abstract

Investigations into the immunogenicity of the prion protein are ongoing. To combat its pathological isoform without affecting the cellular protein is a challenge in prion research. We here summarize the studies in which prion protein peptides have been used for immunization, to thus determine the most immunogenic parts of the prion protein.

Keywords: Prion protein, peptides, epitope prediction, immune response, vaccine


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