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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

A Short and Efficient Synthesis of the Selective H4 Receptor Agonist 4- Methylhistamine

Author(s): Mirko Rivara, Valentina Zuliani, Pier V. Plazzi and Fabrizio Bordi

Volume 6, Issue 1, 2009

Page: [88 - 89] Pages: 2

DOI: 10.2174/157017809787003223

Price: $65

Abstract

An efficient synthesis of the selective H4 receptor agonist 4-methylhistamine is described. This approach can be used to prepare, without purification steps and in high yield, significant quantities of the product, useful as pharmacological tool to investigate the physiological roles of the histamine H4 receptor.

Keywords: 4-methylhistamine, histamine, H4-receptor, n-butyllithium, H4-agonist, yield


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