Abstract
A number of study have suggested a relationship between Helicobacter pylori infection and oxidative stress in the gastric epithelium. The oxidant- induced changes in zinc, iron, and vitamin C increase susceptibility to oxidative injury. Understanding of pathophysiologic mechanisms may provide new therapeutic strategies in treatment of oxidative injury of mucosa.
Keywords: Helicobacter pylori, zinc, iron, vitamin C, oxidative stress
Mini-Reviews in Medicinal Chemistry
Title: Helicobacter Pylori, Zinc and Iron in Oxidative Stress-Induced Injury of Gastric Mucosa
Volume: 9 Issue: 1
Author(s): J. Dovhanj, K. Kljaic, K. Dodig-Curkovic, M. Curkovic, M. Volarevic and K. Marjanovic
Affiliation:
Keywords: Helicobacter pylori, zinc, iron, vitamin C, oxidative stress
Abstract: A number of study have suggested a relationship between Helicobacter pylori infection and oxidative stress in the gastric epithelium. The oxidant- induced changes in zinc, iron, and vitamin C increase susceptibility to oxidative injury. Understanding of pathophysiologic mechanisms may provide new therapeutic strategies in treatment of oxidative injury of mucosa.
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Dovhanj J., Kljaic K., Dodig-Curkovic K., Curkovic M., Volarevic M. and Marjanovic K., Helicobacter Pylori, Zinc and Iron in Oxidative Stress-Induced Injury of Gastric Mucosa, Mini-Reviews in Medicinal Chemistry 2009; 9 (1) . https://dx.doi.org/10.2174/138955709787001767
DOI https://dx.doi.org/10.2174/138955709787001767 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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