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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Trick-or-Treat: Dietary Lipids and Host Resistance to Infectious Disease

Author(s): E. Anes and L. Jordao

Volume 8, Issue 14, 2008

Page: [1452 - 1458] Pages: 7

DOI: 10.2174/138955708786786525

Price: $65

Abstract

The increased intake of omega-6 fatty acids together with the widely use of omega-3 supplements in Western diets can affect the host defence against infectious diseases. In the present review we focused on the impact of these fatty acids on salmonella and mycobacteria infection models in animals or in cell cultures. Particular attention was given to the molecular mechanisms involved.

Keywords: Omega-3 or -6 fatty acids, tuberculosis, inflammation, malnutrition, intracellular pathogens, actin assembly


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