Abstract
This review article describes the current TB drugs, their merits and demerits as well as the new promising anti- TB agents such as diarylquinolines, oxazolidinones and nitroimdiazoles. It also includes the future development of new antitubercular agents according to the potential drug targets of Mycobacterium tuberculosis and structure-activity relationship studies on important anti-TB drugs.
Keywords: Tuberculosis, Mycobacterium tuberculosis, anti-tubercular drugs, drug targets, structure-activity relationship
Mini-Reviews in Medicinal Chemistry
Title: Recent Developments in Antitubercular Drugs
Volume: 8 Issue: 14
Author(s): Pallavi Ahirrao
Affiliation:
Keywords: Tuberculosis, Mycobacterium tuberculosis, anti-tubercular drugs, drug targets, structure-activity relationship
Abstract: This review article describes the current TB drugs, their merits and demerits as well as the new promising anti- TB agents such as diarylquinolines, oxazolidinones and nitroimdiazoles. It also includes the future development of new antitubercular agents according to the potential drug targets of Mycobacterium tuberculosis and structure-activity relationship studies on important anti-TB drugs.
Export Options
About this article
Cite this article as:
Ahirrao Pallavi, Recent Developments in Antitubercular Drugs, Mini-Reviews in Medicinal Chemistry 2008; 8 (14) . https://dx.doi.org/10.2174/138955708786786516
DOI https://dx.doi.org/10.2174/138955708786786516 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
Call for Papers in Thematic Issues
Bioprospecting of Natural Products as Sources of New Multitarget Therapies
According to the Convention on Biological Diversity, bioprospecting is the exploration of biodiversity and indigenous knowledge to develop commercially valuable products for pharmaceutical and other applications. Bioprospecting involves searching for useful organic compounds in plants, fungi, marine organisms, and microorganisms. Natural products traditionally constituted the primary source of more than ...read more
Computational Frontiers in Medicinal Chemistry
The thematic issue "Computational Frontiers in Medicinal Chemistry" provides a robust platform for delving into state-of-the-art computational methodologies and technologies that significantly propel advancements in medicinal chemistry. This edition seeks to amalgamate top-tier reviews spotlighting the latest trends and breakthroughs in the fusion of computational approaches, including artificial intelligence (AI) ...read more
Natural Products and Dietary Supplements in Alleviation of Metabolic, Cardiovascular, and Neurological Disorders
Metabolic disorders like diabetes, obesity, inflammation, oxidative stress, cancer etc, cardiovascular disorders like angina, myocardial infarction, congestive heart failure etc as well as neurological disorders like Alzheimer?s, Parkinson?s, Epilepsy, Depression, etc are the global burden. They covered the major segment of the diseases and disorders from which the human community ...read more
Natural Products in Drug Discovery
Natural products have always been one of the important ways of drug discovery due to their novel skeleton and diverse functional group characteristics. According to statistics, between 1981 and 2019, the FDA approved a total of 1,394 small molecule drugs for marketing, of which 930 marketed drugs originated from the ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Biomedical Nano Tools: A Potential New Paradigm for Immunoassays and Immune Detection
Current Nanomedicine Pharmacophore-based Screening for Identification of Human Acyl-CoA Cholesterol Acyltransferase Inhibitors: An In-silico Study
Letters in Drug Design & Discovery The Role of Autophagy in the Gut Pathogens Clearance and Evasion
Current Protein & Peptide Science Pharmacological Innovations for Posttraumatic Stress Disorder and Medication- Enhanced Psychotherapy
Current Pharmaceutical Design Novel Applications of Recombinant Lactic Acid Bacteria in Therapy and in Metabolic Engineering
Recent Patents on Biotechnology <i>Enoyl-Acyl Carrier Protein Reductase (INHA)</i>: A Remarkable Target to Exterminate Tuberculosis
Anti-Infective Agents Synthesis, Reactions and Biological Evaluation of 3-Amino-6- (subs.)thieno[2,3-b]pyridine-2-carbohydrazides
Current Bioactive Compounds Application of Sugar-Base Anhydro Bridge for Modification of Nucleosides in the 2’- and/or 3’-Positions - Revisited
Current Organic Chemistry Meet Our Editorial Board Member
Current Medicinal Chemistry Nanomedicine: Magnetic Nanoparticles and their Biomedical Applications
Current Medicinal Chemistry Laboratory Techniques for Human Viral Encephalitis Diagnosis
Infectious Disorders - Drug Targets Peptide Deformylase: A New Target in Antibacterial, Antimalarial and Anticancer Drug Discovery
Current Medicinal Chemistry Dietary Antioxidants: Immunity and Host Defense
Current Topics in Medicinal Chemistry The Synthetic Potential and Chemical Aspects of the Gewald Reaction: Application in the Preparation of 2-Aminothiophenes and Related Heterocycles
Current Organic Synthesis Etiopathogenesis, Classical Immunotherapy and Innovative Nanotherapeutics for Inflammatory Neurological Disorders
Current Nanoscience An Update on Natural Products with Carbonic Anhydrase Inhibitory Activity
Current Pharmaceutical Design Telemedicine, Genomics and Personalized Medicine: Synergies and Challenges
Current Pharmacogenomics and Personalized Medicine Properties and Potency of Small Molecule Agents for Treatment of Mycobacterium Tuberculosis Infections of the Central Nervous System
Central Nervous System Agents in Medicinal Chemistry Bacterial Proteases in Disease – Role in Intracellular Survival, Evasion of Coagulation/ Fibrinolysis Innate Defenses, Toxicoses and Viral Infections
Current Pharmaceutical Design Advances of Bioinformatics Applied to Development and Evaluation of Boron-Containing Compounds
Current Organic Chemistry