Abstract
Perinatal brain injury is an important cause of both early and long term morbidity and mortality. The pathophysiology of perinatal brain injury is complex, and often gestation dependent. Ultrasound has traditionally been the imaging modality of choice used to diagnose these lesions; however, the advent of Magnetic Resonance Imaging (MRI) has improved diagnosis and has enabled the correlation of lesions in the neonatal period with longer term neurodevelopmental sequelae. This review aims to address injury in both the term and pre-term brain, its relationship with long term outcome as well as discussing potential treatment strategies which may be deployed in the future.
Keywords: Perinatal brain injury, pre-term, neonatal outcome, hypoxia, ischemia
Current Pediatric Reviews
Title: Perinatal Brain Injury
Volume: 4 Issue: 2
Author(s): Sailesh Kumar, Lisa Story and Mellisa Damodaram
Affiliation:
Keywords: Perinatal brain injury, pre-term, neonatal outcome, hypoxia, ischemia
Abstract: Perinatal brain injury is an important cause of both early and long term morbidity and mortality. The pathophysiology of perinatal brain injury is complex, and often gestation dependent. Ultrasound has traditionally been the imaging modality of choice used to diagnose these lesions; however, the advent of Magnetic Resonance Imaging (MRI) has improved diagnosis and has enabled the correlation of lesions in the neonatal period with longer term neurodevelopmental sequelae. This review aims to address injury in both the term and pre-term brain, its relationship with long term outcome as well as discussing potential treatment strategies which may be deployed in the future.
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Cite this article as:
Kumar Sailesh, Story Lisa and Damodaram Mellisa, Perinatal Brain Injury, Current Pediatric Reviews 2008; 4 (2) . https://dx.doi.org/10.2174/157339608784461981
DOI https://dx.doi.org/10.2174/157339608784461981 |
Print ISSN 1573-3963 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6336 |
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