A Simple and Efficient One-Pot Synthesis of Spirooxindoles in Water Under Microwave Irradiation Conditions

Title: A Simple and Efficient One-Pot Synthesis of Spirooxindoles in Water Under Microwave Irradiation Conditions

Volume: 5 Issue: 4

Author(s): Song-Lei Zhu, Shun-Jun Ji, Kai Zhao and Yong Zhang

Affiliation:

Keywords: Spirooxindoles, three-component synthesis, microwave irradiation, aqueous media

Abstract: A simple and efficient method for the synthesis of spirooxindoles derivatives by one-pot reactions of isatins, activated methylene reagents and activated carbonyl compounds in water under microwave irradiation was reported. This protocol has the advantages of short reaction time, high yields, easy work-up procedure and environmentally benign characters.

Cite this article as:

Zhu Song-Lei, Ji Shun-Jun, Zhao Kai and Zhang Yong, A Simple and Efficient One-Pot Synthesis of Spirooxindoles in Water Under Microwave Irradiation Conditions, Letters in Organic Chemistry 2008; 5 (4) . https://dx.doi.org/10.2174/157017808784049489