An Efficient One-Pot, Two-Step Synthesis of Cyclobuxophyllinine M from Cyclovirobuxine D in Aqueous Media

Title: An Efficient One-Pot, Two-Step Synthesis of Cyclobuxophyllinine M from Cyclovirobuxine D in Aqueous Media

Volume: 5 Issue: 2

Author(s): Min Ji, Hai-Feng Liu, Xiao-Qing Wu, Yan-Bing Duan and Bin Gu

Affiliation:

Keywords: Jones oxidation, Ruschig degradation, cyclobuxophyllinine M, cyclovirobuxine D, aqueous media

Abstract: A highly efficient one-pot, two-step sequential process consisting of modified Jones oxidation of aqueous cyclovirobuxine D acetate followed by Ruschig degradation after pH regulation with saturated aqueous NaOH, provided cyclobuxophyllinine M in high yield and in a single geometrical isomeric form.

Cite this article as:

Ji Min, Liu Hai-Feng, Wu Xiao-Qing, Duan Yan-Bing and Gu Bin, An Efficient One-Pot, Two-Step Synthesis of Cyclobuxophyllinine M from Cyclovirobuxine D in Aqueous Media, Letters in Organic Chemistry 2008; 5 (2) . https://dx.doi.org/10.2174/157017808783743920