Generic placeholder image

Protein & Peptide Letters

Editor-in-Chief

ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

EPITOPE-PARATOPE RECOGNITION BY KNOWLEDGE BASED CORRELATION MAPPING USING HOPFIELD NETWORK

Author(s): Rajani R. Joshi

Volume 8, Issue 4, 2001

Page: [257 - 264] Pages: 8

DOI: 10.2174/0929866013409418

Price: $65

Abstract

The knowledge based correlation mapping (KBCM) is devised here as a unified measure of the information on antigen-antibody complexes available in the Protein Data Banks. This mapping is estimated from a random training sample using a Hopfield Network while representing the epitope and paratope in a complex as 3-dimensional attributed graphs. Identification of paratopes on immunoglobulins against given epitopes is carried out using pattern matching on Hopfield Network with the help of the KBCM.

Keywords: EPITOPE-PARATOPE, knowledge based correlation mapping (KBCM), Epitope, Paratope, immunoglobulins


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy