Abstract
It is suggested that the interactions between the hydrophobic C-H groups of carbohydrate residues and the p-electron systems of aromatic amino-acid residues play an important role in the ligand-recognition function of carbohydrate-binding proteins. This review focuses on our recent structural and functional studies of human lysozyme and hevein-domain type lectins (wheat-germ agglutinin and Ac-AMP2) aimed at understanding how CH / π interactions are involved in the actual binding events.
Keywords: interaction, carbohydrate binding protein, cbp interaction
Protein & Peptide Letters
Title: The Importance of Ch / π Interactions to the Function of Carbohydrate Binding Proteins
Volume: 9 Issue: 3
Author(s): Michiro Muraki
Affiliation:
Keywords: interaction, carbohydrate binding protein, cbp interaction
Abstract: It is suggested that the interactions between the hydrophobic C-H groups of carbohydrate residues and the p-electron systems of aromatic amino-acid residues play an important role in the ligand-recognition function of carbohydrate-binding proteins. This review focuses on our recent structural and functional studies of human lysozyme and hevein-domain type lectins (wheat-germ agglutinin and Ac-AMP2) aimed at understanding how CH / π interactions are involved in the actual binding events.
Export Options
About this article
Cite this article as:
Muraki Michiro, The Importance of Ch / π Interactions to the Function of Carbohydrate Binding Proteins, Protein & Peptide Letters 2002; 9 (3) . https://dx.doi.org/10.2174/0929866023408751
DOI https://dx.doi.org/10.2174/0929866023408751 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
“Epileptic Encephalopathy” of Infancy and Childhood: Electro-Clinical Pictures and Recent Understandings
Current Neuropharmacology A New Frontier in the Treatment of Cancer: NK-1 Receptor Antagonists
Current Medicinal Chemistry Parenting Issues in Mothers with Schizophrenia
Current Women`s Health Reviews Highly Effective Synthesis of 1-thioamidoalkyl-2-naphthols and Tetrahydropyridines Using a Nanostructured Silica-based Catalyst Under Mild Conditions
Combinatorial Chemistry & High Throughput Screening Monoclonal Antibody “Gold Rush”
Current Medicinal Chemistry Genetic Insights into Sporadic Parkinson's Disease Pathogenesis
Current Genomics A Critical and Comprehensive Insight on Heme Oxygenase and Related Products Including Carbon Monoxide, Bilirubin, Biliverdin and Ferritin in Type-1 and Type-2 Diabetes
Current Pharmaceutical Design Cell Reprogramming: A New Chemical Approach to Stem Cell Biology and Tissue Regeneration
Current Pharmaceutical Biotechnology Urinary Tract Tumors, Biology and Risk for Artificial Sweeteners Use with Particular Emphasis on some South American Countries
Current Nutrition & Food Science Obstructive Sleep Apnea and Autoimmune Rheumatic Disease: Is there Any Link?
Inflammation & Allergy - Drug Targets (Discontinued) Antiinflammatory Activity of Melatonin in Central Nervous System
Current Neuropharmacology Preface (New Research Frontiers and Advances in Drug Addiction)
Current Neuropharmacology The Two Faces of Interleukin-17A in Atherosclerosis
Current Drug Targets EEG Correlates of Cognitive Functions and Neuropsychiatric Disorders: A Review of Oscillatory Activity and Neural Synchrony Abnormalities
Current Psychiatry Research and Reviews Correlation of Alzheimer-like Tau Hyperphosphorylation and fMRI Bold Intensity
Current Alzheimer Research The Pharmacological Control of Neuronal Excitability in the Retinal Spreading Depression Model of Migraine
Current Medicinal Chemistry Drug Metabolism as an Object of Computational Analysis by the Monte Carlo Method
Current Drug Metabolism Meet Our Editorial Board Member:
Medicinal Chemistry It is All About Proteases: From Drug Delivery to In Vivo Imaging and Photomedicine
Current Medicinal Chemistry Alcohol Enhances HIV Infection of Cord Blood Monocyte-Derived Macrophages
Current HIV Research