Abstract
Chagas disease is a major parasitic problem in developing countries in Central and South America. Chemotherapy for such disease is still insufficient and not effective in its chronic part. Many efforts have been made in recent years to know more about possible new biochemical targets to design new selective drugs. This paper reviews old therapeutic approaches -Nifurtimox, Benznidazole and related compounds- and the latest rationally developed drugs that prove to be active against different parasitic forms
Keywords: chemotherapy of chagas disease
Current Topics in Medicinal Chemistry
Title: Chemotherapy of Chagas Disease: Status and New Developments
Volume: 2 Issue: 11
Author(s): Hugo Cerecetto and Mercedes Gonzalez
Affiliation:
Keywords: chemotherapy of chagas disease
Abstract: Chagas disease is a major parasitic problem in developing countries in Central and South America. Chemotherapy for such disease is still insufficient and not effective in its chronic part. Many efforts have been made in recent years to know more about possible new biochemical targets to design new selective drugs. This paper reviews old therapeutic approaches -Nifurtimox, Benznidazole and related compounds- and the latest rationally developed drugs that prove to be active against different parasitic forms
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Cite this article as:
Cerecetto Hugo and Gonzalez Mercedes, Chemotherapy of Chagas Disease: Status and New Developments, Current Topics in Medicinal Chemistry 2002; 2 (11) . https://dx.doi.org/10.2174/1568026023393066
DOI https://dx.doi.org/10.2174/1568026023393066 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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