Synthesis of 8,16-Ethanoretinals and Their Interactions with Apoprotein of Phoborhodopsin from Natronobacterium pharaonis

Title: Synthesis of 8,16-Ethanoretinals and Their Interactions with Apoprotein of Phoborhodopsin from Natronobacterium pharaonis

Volume: 1 Issue: 1

Author(s): Akimori Wada, Yoshimi Takakura, Kenta Yamazaki, Tetsuo Takahashi and Masayoshi Ito

Affiliation:

Keywords: ethanoretinal, retinal analog, phoborhodopsin, chromophore, s-trans conformation

Abstract: Several 8,16-Ethanoretinals 3 were synthesized from cyclohexanones. From the binding experiments of these analogs with apoprotein of phoborhodopsin, it was found that retinal was incorporated as 6s-trans conformation in the protein and the fine structure in absorption spectra of pigments were dependent on the coplanarity of the conjugated polyene structure in the chromophore.

Cite this article as:

Wada Akimori, Takakura Yoshimi, Yamazaki Kenta, Takahashi Tetsuo and Ito Masayoshi, Synthesis of 8,16-Ethanoretinals and Their Interactions with Apoprotein of Phoborhodopsin from Natronobacterium pharaonis, Letters in Organic Chemistry 2004; 1 (1) . https://dx.doi.org/10.2174/1570178043488789