Abstract
1,4-Dichloro-1,4-disubstituted-2,3-diaza-1,3-butadiene 1 undergo cyclodechlorination in presence of Be metal to form cyclazines 3a. Reaction of 1 with Cu, Zn and Mn metals results in formation of nitriles 2. Cyclazines 3 on further oxidation with H2O2 in CH3COOH form NO donors, 1,2-dioxides 4.
Keywords: cyclodechlorination, chlorination, nitriles, cyclazines, no donors
Letters in Organic Chemistry
Title: Metal Mediated Dechlorination - A New Route to Nitriles
Volume: 1 Issue: 1
Author(s): V. K. Tandon and R. B. Chhor
Affiliation:
Keywords: cyclodechlorination, chlorination, nitriles, cyclazines, no donors
Abstract: 1,4-Dichloro-1,4-disubstituted-2,3-diaza-1,3-butadiene 1 undergo cyclodechlorination in presence of Be metal to form cyclazines 3a. Reaction of 1 with Cu, Zn and Mn metals results in formation of nitriles 2. Cyclazines 3 on further oxidation with H2O2 in CH3COOH form NO donors, 1,2-dioxides 4.
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Cite this article as:
Tandon K. V. and Chhor B. R., Metal Mediated Dechlorination - A New Route to Nitriles, Letters in Organic Chemistry 2004; 1 (1) . https://dx.doi.org/10.2174/1570178043488680
DOI https://dx.doi.org/10.2174/1570178043488680 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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