Chiral Linker 1. A Novel Chiral Auxiliary Derived from m-Hydrobenzoin as Enantiomerically Pure Linker for Solid Phase Organic Chemistry

Title: Chiral Linker 1. A Novel Chiral Auxiliary Derived from m-Hydrobenzoin as Enantiomerically Pure Linker for Solid Phase Organic Chemistry

Volume: 1 Issue: 3

Author(s): P. Gaertner, C. Schuster and M. Knollmueller

Affiliation:

Keywords: polymer support, chiral auxiliary, linker, enolate, alkylation, hydrobenzoin

Abstract: The synthesis and utility of a novel, m-hydrobenzoin derived chiral auxiliary in stereoselective α- alkylation reactions using convenient solution chemistry as well as the attachment of an analogous system onto a solid support and its application as a dual chiral auxiliary and linker is described.

Cite this article as:

Gaertner P., Schuster C. and Knollmueller M., Chiral Linker 1. A Novel Chiral Auxiliary Derived from m-Hydrobenzoin as Enantiomerically Pure Linker for Solid Phase Organic Chemistry, Letters in Organic Chemistry 2004; 1 (3) . https://dx.doi.org/10.2174/1570178043400901