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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Cellular and Physiological Effects of Short-Chain Fatty Acids

Author(s): Steven J. Miller

Volume 4, Issue 8, 2004

Page: [839 - 845] Pages: 7

DOI: 10.2174/1389557043403288

Price: $65

Abstract

Short chain fatty acids (SCFA) have multiple in vivo and in vitro effects including cell cycle arrest and induction of protein synthesis, differentiation, and apoptosis. Butyrate or derivatives have promise for treating inflammatory bowel disease and colon cancer. Genomic and proteomic analysis have generated new knowledge on function and applications for SCFA.

Keywords: short chain fatty acids, butyrate, inflammation, cancer, colon and fiber


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