Abstract
Imidazopyridines and imidazopyrimidines have been prepared and tested for their antibacterial activity in vitro. Structure activity relationship studies indicate (SAR) that a modulation of both natures of arm in position 3 and atom in position 8 of these compounds has a direct impact on the antibacterial activity.
Keywords: Imidazo[1,2-a]pyrimidines., imidazo[1,2-a]pyridines, antibacterial agents, functionalised arms, n-ligands, mycobacterium tuberculosis
Letters in Drug Design & Discovery
Title: Armed Imidazo [1,2-a] Pyrimidines (Pyridines): Evaluation of Antibacterial Activity
Volume: 1 Issue: 3
Author(s): A. Anaflous, N. Benchat, M. Mimouni, S. Abouricha, T. Ben-Hadda, B. El-Bali, A. Hakkou and B. Hacht
Affiliation:
Keywords: Imidazo[1,2-a]pyrimidines., imidazo[1,2-a]pyridines, antibacterial agents, functionalised arms, n-ligands, mycobacterium tuberculosis
Abstract: Imidazopyridines and imidazopyrimidines have been prepared and tested for their antibacterial activity in vitro. Structure activity relationship studies indicate (SAR) that a modulation of both natures of arm in position 3 and atom in position 8 of these compounds has a direct impact on the antibacterial activity.
Export Options
About this article
Cite this article as:
Anaflous A., Benchat N., Mimouni M., Abouricha S., Ben-Hadda T., El-Bali B., Hakkou A. and Hacht B., Armed Imidazo [1,2-a] Pyrimidines (Pyridines): Evaluation of Antibacterial Activity, Letters in Drug Design & Discovery 2004; 1 (3) . https://dx.doi.org/10.2174/1570180043398885
DOI https://dx.doi.org/10.2174/1570180043398885 |
Print ISSN 1570-1808 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-628X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Synthesis and Evaluation of New 5-methylisoxazole-3-carboxamide Derivatives as Antitubercular Agents
Anti-Infective Agents Synthesis and Evaluation of New Thiazole Derivatives as Potential Antimicrobial Agents
Letters in Drug Design & Discovery Antimicrobial Peptides with pH-Dependent Activity and Alkaline Optima: Their Origins, Mechanisms of Action and Potential Applications
Current Protein & Peptide Science Tolerance Induction by Gene Transfer to Lymphocytes
Current Gene Therapy Editorial [Hot Topic:Protein targets for development of drugs against Mycobacterium tuberculosis (Guest Editor: Walter Filgueira de Azevedo)]
Current Medicinal Chemistry Vertebral Lesions from AIDS-Related Kaposi's Sarcoma
Current HIV Research Synthesis and Biological Activity of Fused Heteropolycyclic Systems Containing an Indole Moiety
Current Organic Synthesis Antibacterial Activity of Lipophilic Fluoroquinolone Derivatives
Medicinal Chemistry Chronic Stress and Diabetes Mellitus: Interwoven Pathologies
Current Diabetes Reviews Isoniazid: Metabolic Aspects and Toxicological Correlates
Current Drug Metabolism B-Cells and the Use of Non-Human Primates for Evaluation of HIV Vaccine Candidates
Current HIV Research Nose-to-Brain Drug Delivery by Nanoparticles in the Treatment of Neurological Disorders
Current Medicinal Chemistry Pharmacological Drug Delivery Strategies for Improved Therapeutic Effects: Recent Advances
Current Pharmaceutical Design Targeting Tuberculosis: A Glimpse of Promising Drug Targets
Mini-Reviews in Medicinal Chemistry Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase (Dxr): A Review of the Synthesis and Biological Evaluation of Recent Inhibitors
Current Topics in Medicinal Chemistry Recent Advances in the Development of Small-Molecular Inhibitors Target HIV Integrase-LEDGF/p75 Interaction
Mini-Reviews in Medicinal Chemistry New Aminoacyl-tRNA Synthetase Inhibitors as Antibacterial Agents
Current Drug Targets - Infectious Disorders Anti-Infective Protective Properties of S100 Calgranulins
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Trends in the Design and Application of Optical Chemosensors in Pharmaceutical and Biomedical Analysis
Current Pharmaceutical Analysis Small Heat Shock Proteins and Protein-Misfolding Diseases
Current Pharmaceutical Biotechnology