A Simple Approach to DC-Cholesterol, its Analogues and Vitamin D-Based Cationic Lipids for Gene Therapy

Title: A Simple Approach to DC-Cholesterol, its Analogues and Vitamin D-Based Cationic Lipids for Gene Therapy

Volume: 2 Issue: 1

Author(s): Armandodoriano Bianco, Francesco Bonadies, Raffaella Napolitano and Giancarlo Ortaggi

Affiliation:

Keywords: cationic lipids, gene therapy, dc-cholesterol, modified curtius reaction, dc-vitamin d-based cationic lipids

Abstract: An improved synthesis of DC-Cholesterol, its analogues and Vitamin D-based lipids for the preparation of liposomes in gene therapy, is described. This synthetic strategy affords significative increase in the yields of DC-Cholesterol and its analogs.

Cite this article as:

Bianco Armandodoriano, Bonadies Francesco, Napolitano Raffaella and Ortaggi Giancarlo, A Simple Approach to DC-Cholesterol, its Analogues and Vitamin D-Based Cationic Lipids for Gene Therapy, Letters in Organic Chemistry 2005; 2 (1) . https://dx.doi.org/10.2174/1570178053399921