Abstract
Virtual screening encompasses several computational approaches which have proven valuable for identifying novel leads. These approaches rely on available information. Herein, we review recent successful applications of virtual screening. The extension of virtual screening methodologies to target families is also briefly discussed.
Keywords: virtual screening, chemical biology, chemogenomics, lead discovery, similarity searching, pharmacophore, data mining, docking
Mini-Reviews in Medicinal Chemistry
Title: Knowledge-Driven Lead Discovery
Volume: 5 Issue: 11
Author(s): Bernard Pirard
Affiliation:
Keywords: virtual screening, chemical biology, chemogenomics, lead discovery, similarity searching, pharmacophore, data mining, docking
Abstract: Virtual screening encompasses several computational approaches which have proven valuable for identifying novel leads. These approaches rely on available information. Herein, we review recent successful applications of virtual screening. The extension of virtual screening methodologies to target families is also briefly discussed.
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Cite this article as:
Pirard Bernard, Knowledge-Driven Lead Discovery, Mini-Reviews in Medicinal Chemistry 2005; 5 (11) . https://dx.doi.org/10.2174/138955705774575237
DOI https://dx.doi.org/10.2174/138955705774575237 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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