The Chiral N-Monosubstituted 1,2-diphenyl-2-aminoethanols Promoted Enantioselective Diethylzinc Addition to In Situ Formed Imines

Title: The Chiral N-Monosubstituted 1,2-diphenyl-2-aminoethanols Promoted Enantioselective Diethylzinc Addition to In Situ Formed Imines

Volume: 2 Issue: 7

Author(s): W.- W. Yang, L.- F. Cun, Y.- G. Zhi, A.- Q. Mi, Y.- Z. Jiang and L.- Z. Gong

Affiliation:

Keywords: asymmetric catalysis, amino alcohols, diethylzinc addition, imines

Abstract: The use of easily accessible N-monosubstituted 1,2-diphenyl-2-aminoethanols as ligands to promote the asymmetric addition of diethylzinc to alkyl- and arylimines generated in situ from the precursors provided optically active N-diphenylphosphinylamines with enantioselectivities of up to 96% ee.

Cite this article as:

Yang W. W.-, Cun F. L.-, Zhi G. Y.-, Mi Q. A.-, Jiang Z. Y.- and Gong Z. L.-, The Chiral N-Monosubstituted 1,2-diphenyl-2-aminoethanols Promoted Enantioselective Diethylzinc Addition to In Situ Formed Imines, Letters in Organic Chemistry 2005; 2 (7) . https://dx.doi.org/10.2174/157017805774296939