Abstract
Celiac disease is a genetically determined autoimmune disorder induced by an environmental agent, gluten. The disease involves the development of a T-cell mediated inflammatory reaction to ingested gluten in the small intestine that results in villous atrophy. The manifestations of the disease are varied. Patients may be critically ill due to a severe malabsorption syndrome or asymptomatic. The reason for the varied phenotypic expression of the disease is unclear. The mainstay of therapy is a gluten-free diet that may be a testing endeavor in this culture.
Keywords: gluten sensitive enteropathy, HLA-DQ2, IgA endomysial antibody, gluten-free diet, autoimmune diseases, Selective IgA deficiency
Current Nutrition & Food Science
Title: Celiac Disease: An Emerging Epidemic
Volume: 1 Issue: 3
Author(s): Peter H.R. Green and Anne R. Lee
Affiliation:
Keywords: gluten sensitive enteropathy, HLA-DQ2, IgA endomysial antibody, gluten-free diet, autoimmune diseases, Selective IgA deficiency
Abstract: Celiac disease is a genetically determined autoimmune disorder induced by an environmental agent, gluten. The disease involves the development of a T-cell mediated inflammatory reaction to ingested gluten in the small intestine that results in villous atrophy. The manifestations of the disease are varied. Patients may be critically ill due to a severe malabsorption syndrome or asymptomatic. The reason for the varied phenotypic expression of the disease is unclear. The mainstay of therapy is a gluten-free diet that may be a testing endeavor in this culture.
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Cite this article as:
Green H.R. Peter and Lee R. Anne, Celiac Disease: An Emerging Epidemic, Current Nutrition & Food Science 2005; 1 (3) . https://dx.doi.org/10.2174/157340105774574811
DOI https://dx.doi.org/10.2174/157340105774574811 |
Print ISSN 1573-4013 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3881 |
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