Abstract
The patients psychiatric diagnoses play a large role in the design and outcome of psychopharmacology clinical trials. Among antidepressant trials, magnitude of placebo response, initial severity of depression, dosing regimen, number of treatment arms and duration of trial, choice of rating scales, and sex of the patient may influence antidepressant trial outcome.
Keywords: investigational psychopharmacological agent, Antidepressant, placebo, Clinical Trials, obsessive compulsive disorder (OCD)
Letters in Drug Design & Discovery
Title: Design Features that Affect Psychopharmacology Trials
Volume: 2 Issue: 7
Author(s): Arif Khan and Kelly Schwartza
Affiliation:
Keywords: investigational psychopharmacological agent, Antidepressant, placebo, Clinical Trials, obsessive compulsive disorder (OCD)
Abstract: The patients psychiatric diagnoses play a large role in the design and outcome of psychopharmacology clinical trials. Among antidepressant trials, magnitude of placebo response, initial severity of depression, dosing regimen, number of treatment arms and duration of trial, choice of rating scales, and sex of the patient may influence antidepressant trial outcome.
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Cite this article as:
Khan Arif and Schwartza Kelly, Design Features that Affect Psychopharmacology Trials, Letters in Drug Design & Discovery 2005; 2 (7) . https://dx.doi.org/10.2174/157018005774479140
DOI https://dx.doi.org/10.2174/157018005774479140 |
Print ISSN 1570-1808 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-628X |
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