Stereoselective Synthesis of the Core of Naturally Occurring Anti-HIV Isolitseane B

Title: Stereoselective Synthesis of the Core of Naturally Occurring Anti-HIV Isolitseane B

Volume: 4 Issue: 4

Author(s): Paul Bremond, Elodie Girardeau, Yoann Coquerel and Jean Rodriguez

Affiliation:

Keywords: Acetal, Pauson-Khand, anti-HIV, total synthesis, natural products

Abstract: A key intermediate in the total synthesis of naturally occurring anti-HIV Isolitseane B has been prepared in five steps from propargyl alcohol, featuring a highly selective mono-transacetalization and a stereoselective Pauson-Khand cyclization.

Cite this article as:

Paul Bremond , Elodie Girardeau , Yoann Coquerel and Jean Rodriguez , Stereoselective Synthesis of the Core of Naturally Occurring Anti-HIV Isolitseane B, Letters in Organic Chemistry 2007; 4 (4) . https://dx.doi.org/10.2174/157017807781024237