Abstract
The majority of current smokers in the U.S. also have at least one comorbid psychiatric illness. Looking at commons mechanisms of nicotine dependence and psychiatric disorders of hedonic regulation reveals nicotinic acetylcholine receptors and the glycine site on NMDA receptors as potential targets for pharmacological treatment of these disorders.
Keywords: Nicotine dependence, Drug targets, Schizophrenia, Anhedonia, Nicotinic receptors, Glycine site/NMDA receptor
Letters in Drug Design & Discovery
Title: Nicotinic and Glycinergic Medications for Disorders of Hedonic Regulation
Volume: 4 Issue: 5
Author(s): M.A. Dyer, R.S. Barr and A.E. Evins
Affiliation:
Keywords: Nicotine dependence, Drug targets, Schizophrenia, Anhedonia, Nicotinic receptors, Glycine site/NMDA receptor
Abstract: The majority of current smokers in the U.S. also have at least one comorbid psychiatric illness. Looking at commons mechanisms of nicotine dependence and psychiatric disorders of hedonic regulation reveals nicotinic acetylcholine receptors and the glycine site on NMDA receptors as potential targets for pharmacological treatment of these disorders.
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Cite this article as:
Dyer M.A., Barr R.S. and Evins A.E., Nicotinic and Glycinergic Medications for Disorders of Hedonic Regulation, Letters in Drug Design & Discovery 2007; 4 (5) . https://dx.doi.org/10.2174/157018007780867852
DOI https://dx.doi.org/10.2174/157018007780867852 |
Print ISSN 1570-1808 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-628X |
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